Real Betis are undefeated in four matches when they host Utrecht for their fifth match in the UEFA Europa League.
Match Replays
Rangers are still looking for their first points in the Europa League when they face Braga in their fifth match of the league stage.
Sturm Graz look to build off a draw last time out when they travel to take on Panathinaikos on Matchday 5 of the Europa League.
Malmö travel to England to take on Nottingham Forest, who have lost just once in the first four Europa League matches.
Lyon lost for the first time last time out, but have the chance to bounce back on the road to Maccabi Tel-Aviv.
Stuttgart look to string two wins in a row together when they travel to take on Go Ahead Eagles in the UEFA Europa League.
Basel and Genk could both move into the top eight of the UEFA Europa League with all three points on Matchday 5.
Crvena Zvezda play host to FCSB, who are hoping to end a three-match losing streak in the UEFA Europa League.
RB Salzburg snapped a three-match skid last time out and now take on Bologna, who have lost just once in four Europa League matches.
Freiburg look to continue their run at the top of the Europa League when they take on Viktoria Plzeň during Matchday 5.
Midtjylland are the only perfect team left in the Europa League ahead of a tough trip to a Roma side that won last time out.
Nice need to turn around their Europa League campaign during a tough trip to Porto, who haven't won in their last two matches.